A general rule for data is the more tests performed, or the more information gathered, the higher chance of credibility. The more information you come in contact with, the better picture you will have. The aggregated information of a crowd of people is superior to the individual.
For news this means reading lots of articles and isolating facts you can trust. There is a need to cross reference information to make sure it is correct. Many news sites have started using the word “fact check” but even they often fall short. Snopes is an excellent example of this. Any person or organization worth its salt always needs multiple forms of proof.
Ultimately, one of the best defenses we have against fake news is skepticism and caution. An ability to read between the lines that is developed over time. Even if some high degree of tests come in to indicate something is real — this does not necessarily indicate truth. The crowd does have good aggregate information but it is all too often fooled. Usually there will exist a highly informed minority that is consistently correct about things. If this group of people can be identified, this will provide a step up to ascertaining the truth.